Summary
ID Swiss Botanicals is at the forefront of neurocosmetic innovation, integrating neuroscience into its products to understand and exploit the interactions between the skin and the brain. This approach allows us to discover how our mental and emotional well-being influences our skin. Neurocosmetics uses neuroactive ingredients to precisely target the skin's neural pathways.
THE CBD VectorS™ is a dual-encapsulated multi-neuroactive liposome technology designed to optimize their delivery and efficacy. Used in the Skin Stress Balancer serum, a dry and soluble product, this technology allows for seamless integration into skincare routines without altering textures or fragrances.
Studies show that the CBD VectorS™ has a higher antioxidant capacity than low-dose vitamin E (α-Tocopherol), with a 45% reduction versus 29%. In vitro tests on reconstructed epidermis have demonstrated that CBD VectorS™ improves skin repair, reduces inflammation, and protects against various environmental and chemical stresses. Additionally, VectorS™ CBD increases mitochondrial energy levels by over 300% and reduces skin sensitivity by up to 67%.
Research also confirms that the CBD VectorS™ activates key physiological pathways such as Nrf-2 and TRPV1, thereby enhancing protection against oxidative stress and inflammation.
By increasing cellular energy, reducing inflammation and protecting against various stresses, the CBD VectorS™ represents a significant advance in neurocosmetics.
The future of cosmetics is moving towards holistic and scientific beauty solutions, harmonizing the interactions between body and mind. This approach promises to transform our skincare routine into a truly integrative and enlightened experience, opening new horizons for health and beauty.
Introduction
ID Swiss Botanicals is an innovative brand in the world of neurocosmetics, integrating neuroscience into its products to explore the complex interactions between the skin and the brain. This approach allows us to better understand how our mental and emotional well-being is reflected on our skin. Neurocosmetics uses neuroactive ingredients to specifically target cutaneous neuronal signaling pathways.
THE CBD VectorS™ is a dual-encapsulated multi-neuroactive liposome technology, developed to improve their diffusion and efficacy. Used in the Skin Stress Balancer product, a soluble dry serum, this technology allows for better integration into skin care routines without altering textures or fragrances.
Study results
A. In-tubo antioxidant study
The DPPH test is used to measure the antioxidant activity of compounds. The results showed that the neuroactive compounds CBD VectorS™ have a higher antioxidant capacity than α-Tocopherol (the most antioxidant form of vitamin E) at low doses (EC50 = 1366 µg/mL).
- Antioxidant efficacy :
- At 10µg/mL: a reduction of 45% compared to 29% for α-Tocopherol.
- Conclusion : higher efficacy than α-Tocopherol.
- Double encapsulation by the CBD VectorS™ ensures better stability and bioavailability of neuroactive ingredients.
B. In vitro biomarker study
Tests were carried out on reconstructed epidermis under cell culture conditions to avoid animal testing and invasive methods on human subjects. The effectiveness of the CBD VectorS™ was measured under various stress conditions: UV/IR, urban pollution, and chemical irritation.
- Solar stress conditions (UV/IR) :
- Modulated markers : PDGF-BB, TNFα, TNFβ, TIMP-1, TIMP-2, IL-6SR, IL-8, CCL5.
- Results :
- Increased PDGF-BB, TIMP-1, TIMP-2, IL-6SR & reduced TNFα and TNFβ, showing improved skin repair and protection against extracellular matrix degradation.
- Increased IL-8, indicating an increased but controlled immune response, to repair UV damage.
- Urban pollution conditions :
- Modulated markers : TNFα, TNFβ, TNFRA, IL-1, IL-17, CCL24, IL-8.
- Results :
- Increased CCL24 and IL-8, involved in the recruitment of immune cells, for activation of tissue repair.
- Significant reductions in TNFα, TNFβ, TNFRA, IL-1beta, and IL-17, highlighting anti-inflammatory properties against environmental pollutants.
- Chemical stress conditions (SDS) :
- Modulated markers : IL-1α, IL-1β, TIMP-1, TIMP-2, PDGF-BB.
- Results :
- Increases in PDGF-BB, TIMP-1, TIMP-2, indicating a supportive role in skin repair.
- Significant reductions in IL-1α and IL-1β, demonstrating anti-inflammatory effects post-chemical irritation.
- Basal activity (without stress) :
- Modulated markers : PDGF-BB, CCL5, CCL2, CCL1, IL-6sR.
- Results :
- Significant reduction of CCL1 and CCL2, indicating enhanced anti-inflammatory properties.
- Increased CCL5 and IL-6sR, suggesting positive modulation of immune responses.
- Significant increase in PDGF-BB, implying an exacerbated functional state of cellular repair and an increase in mitochondrial energy levels of more than 300%.
These results demonstrate that the CBD VectorS™ provides robust protection against various environmental and chemical stresses, while improving skin repair and resilience, and reducing skin sensitivity by up to 67%.
In addition, the CBD VectorS™, free from any external stress, soothes the tissues (desensitizing effect) and guarantees additional energy resources (potential preventive and curative effects).
Promising prospects for neurocosmetics
The research of ID Swiss Botanicals illustrate strong antioxidant potential, an ability to increase cellular energy levels without associated toxicity, and positive impacts on inflammation and immune function of the skin in different conditions. CBD VectorS™ activates important physiological pathways such as Nrf-2 and TRPV1, enhancing protection against oxidative stress and inflammation.
- Modulation of TRPV1 receptors :
TRPV1 receptors play a crucial role in temperature regulation and pain perception. By binding to TRPV1 receptors and acting on the endocannabinoid system, CBD improves the condition and appearance of the skin by modulating skin sensitivity and relieving irritation. This modulation helps reduce the perception of painful stimuli, providing a feeling of increased comfort for sensitive skin. It also helps reduce physiological responses to stress, contributing to a general state of well-being.
- Activation of the Nrf-2 pathway :
Nrf-2 regulates the expression of genes involved in defense against oxidative stress, essential for preventing skin damage and premature aging. Stimulation of this pathway improves the regulation of antioxidant enzymes, protecting cells against damage caused by free radicals and environmental aggressions. This regulation also helps strengthen the skin's natural defenses, making it more resistant to external aggressions. This cellular protection pathway is particularly essential for peripheral nerve cells, including sensory neurons. Due to their high energy requirements, these cells produce a significant amount of oxygenated free radicals. In the long term, this activation helps reduce the harmful effects of chronic stress, thus ensuring better protection and greater resilience of nerve cells.
Strengthening the neurocosmetic approach
The importance of neurocosmetics lies in the ability of its products to influence neurocutaneous interactions. The skin, as a major sensory organ, continually communicates with the brain through neural and chemical signals. By harnessing these pathways, neurocosmetic products, such as VectorS™ CBD, go beyond traditional topical care by directly influencing the skin’s neural responses.
Effects on mental and emotional well-being
Neuroactive ingredients such as those used in VectorS™ CBD have calming and soothing effects on the skin, resulting in reduced skin reactivity and improved sensory comfort. These effects are particularly beneficial for those with sensitive or reactive skin, where mental and emotional stress can exacerbate skin conditions.
Impact on neurocutaneous performance
The results demonstrated by CBD VectorS™ show a significant reduction in skin sensitivity by 67%, which is crucial for improving the skin’s tolerance to external aggressions. By increasing mitochondrial energy levels by more than 300%, CBD VectorS™ promotes cellular vitality, thus improving skin resistance and repair.
Holistic integration of beauty and health
ID Swiss Botanicals’ neurocosmetic approach goes beyond improving the appearance of the skin. It also aims to harmonize the interactions between the body and mind, providing a skincare experience that contributes to overall well-being. This holistic approach is essential to meet the needs of modern consumers who are looking for integrative and sustainable beauty solutions.
Conclusion
THE CBD VectorS™ developed by ID Swiss Botanicals represents a significant advancement in neurocosmetics. By increasing cellular energy by over 300%, reducing inflammation and oxidative stress, and promoting tissue repair and regeneration, this innovative product demonstrates how a deep understanding of the interactions between the skin and the brain can be harnessed to improve skin health and overall well-being.
By integrating advanced technologies and neuroactive ingredients, skincare products can now more precisely and effectively target skin needs. The future of cosmetics is moving toward holistic, science-based beauty solutions that not only improve the appearance of the skin, but also overall well-being by harmonizing the interactions between the body and mind. This approach promises to transform skincare routines into truly integrative and enlightened experiences, propelling the industry toward new horizons of health and beauty.
